If the target has not made its move this turn, but is scheduled to use a damage-dealing move, Me First copies that move preemptively and increases the power by 50%. It bypasses accuracy checks to always hit, unless the opponent is in the semi-invulnerable turn of a move such as Dig or Fly. Me First will fail if the target selected a non-damaging move, or if the target already executed its move this turn.
If the target is about to recharge from a move like Frenzy Plant this turn, Me First will copy the move. If a consecutively executed move like Outrage is copied, it will force the user of Me First to use the move for several turns, but the 50% increase in power only applies to the first turn. Me First is unable to copy Struggle, Covet, Thief, Focus Punch, Counter, Mirror Coat, Metal Burst, or moves called by other moves.